Endocrine Abstracts

Introduction: Pregnancy is a state of increased insulin resistance and insulin secretion and reduced hepatic extraction of insulin; thus fasting during pregnancy seems to cause a high risk of morbidity and mortality for the fetus and its mother. This group of diabetic patients is exempt from fasting. However, for young patients or not, Ramadan is accompanied by a change in lifestyle in particular a change in eating habits as well as a disruption of the sleep cycle and a decrea...

Introduction: Uncontrolled hyperglycemia in diabetes is a common cause of microvascular complications, including diabetic nephropathy (DN). Despite improvements in the management of type 2 diabetes (T2DM), diabetic nephropathy is still associated with high morbidity and mortality. The objective of our study is to evaluate the predictive factors of DN in adults with T2DM in order to prevent its development.Patients and Methods: A retrospective study, incl...

Introduction: Maternal overweight is a major risk of gestational diabetes that can impair glycemic control. The objective of our study was to assess the impact of maternal weight status on glycemic control and pregnancy outcomes in patients followed for gestational diabetes.Methods: Our work is a retrospective study, including 182 patients with gestational diabetes followed in the Endocrinology-Diabetology department between January 2016 and January 2022...

Introduction: Fasting during Ramadan very often requires a change in lifestyle for patients and adaptation is not easy in individuals with type 2 diabetes (T2D). Physical activity, sleep duration and sleep time are subject to change during Ramadan, due to changes in the number and times of meals.Study Objectives: This study aims to assess the physical activity and sleep patterns of T2DM patients during Ramadan.Material and Methods:...

Introduction: Diabetic foot osteomyelitis is a frequent complication of a preexisting infected foot wound. It is mostly the consequence of a soft tissue infection that spreads into the bone thus increasing the risk of amputation and the burden of foot care. The aim of this work is to describe the clinical and therapeutic aspect of diabetic foot osteomyelitis in our department.Patients and Methods: It’s a retrospective and descriptive study conducted...

Introduction: Liraglutide has shown several benefits in diabetic patients, both in terms of glycemic profile and metabolic control. The objective of our work is to show the effects of liraglutide on the metabolic profile of obese T2D patients.Materials and methods: This is a prospective study involving 31 obese T2D patients followed at the Department of Endocrinology and Metabolic Diseases CHU IBN ROCHD from January 2018 to December 2022. The data analys...

Introduction: Acromegaly is the set of clinical manifestations induced by chronic exposure to an endogenous excess of growth hormone (GH). Most often, acromegaly is related to GH production by a pituitary adenoma. It may be associated with neuroendocrine tumors of the pancreas as part of multiple endocrine neoplasia type 1 (MEN1). Herein, we described a tumor mimicking a carcinoma of the Ampulla of Vater in a patient with acromegaly.Observation: A 54-yea...

Introduction: Pregnancy in patients with pituitary pathology is a rare and delicate situation. However, risks for the mother and the foetus as well as the consequences of pregnancy on the history of pituitary adenoma require close monitoring.Goals: Illustrate through 5 observations the evolution of pituitary pathology during pregnancy.Observations: 1st patient: 41-year-old followed for somatotropic pituitary macro ...

Introduction: Metabolic disorders caused by acromegaly are responsible for three times the morbidity of the general populationStudy objectives: To analyze the different metabolic complications in acromegalic patients.Materiel and methods: This is a retrospective study of 62 cases of acromegaly followed at the Department of Endocrinology and Metabolic Diseases CHU IBN ROCHD from January 2005 to December 2022. The data analysis was d...

Introduction: Acromegaly is an unusual disease in adolescence. Its diagnosis and management are a challenge in this population. Here we report 2 rare cases of acromegaly in this age group.Patients and Observations: Observation 1: This is a 17 year old patient admitted for acromegaly on pituitary microadenoma measuring 4*3mm who presents a symptomatology made of an accentuation of the growth rate, thin and long limbs, elongated hands and ...